IL16 rabbit pAb
The protein encoded by this gene is a pleiotropic Cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this Cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The Cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Product Specifications
Background
Product Name Alternative
Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF) ]
UniProt
Q14005
Swiss Prot
Q14005
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 900-960
Target
IL16
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
67kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
67kD
Fragment
IgG
Subcellular Location
[Interleukin-16]: Secreted.; [Isoform 1]: Cytoplasm .; [Isoform 3]: Cytoplasm. Nucleus.
Other Product Names
Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF) ]
Gene ID (Human)
3603
Available Sizes
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