POM121 rabbit pAb

This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013],

Product Specifications

Background

UniProt

Q96HA1/A6NF01/A8CG34

Swiss Prot

Q96HA1/A6NF01/A8CG34

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human POM121. AA range:1197-1246

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

125kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

125kD

Fragment

IgG

Subcellular Location

Nucleus, nuclear pore complex . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase. .

Other Product Names

POM121; KIAA0618; NUP121; POM121A; Nuclear envelope pore membrane protein POM 121; Nuclear envelope pore membrane protein POM 121A; Nucleoporin Nup121; Pore membrane protein of 121 kDa; POM121B; Putative nuclear envelope pore membrane prote