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KLF7 rabbit pAb

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipoCytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

Product Specifications

Background

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Product Name Alternative

KLF7; UKLF; Krueppel-like factor 7; Ubiquitous krueppel-like factor

UniProt

O75840

Swiss Prot

O75840

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human KLF7. AA range:171-220

Target

KLF7

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Buffer

-20°C/1 year

Molecular Weight

41kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

41kD

Fragment

IgG

Subcellular Location

Nucleus .

Other Product Names

KLF7; UKLF; Krueppel-like factor 7; Ubiquitous krueppel-like factor

Gene ID (Human)

8609

Available Sizes

Curated Selection

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