ULK1 rabbit pAb

Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells. similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. similarity: Contains 1 protein kinase domain. subunit: Interacts with GABARAP and GABARAPL2. tissue specificity: Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.

Product Specifications

Background

Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily., similarity:Contains 1 protein kinase domain., subunit:Interacts with GABARAP and GABARAPL2., tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.

UniProt

O75385

Swiss Prot

O75385

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human ULK1.

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome. .

Other Product Names

ULK1; KIAA0722; Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; hATG1; Unc-51-like kinase 1

Gene ID (Human)

8408

Available Sizes

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