Cep97 rabbit pAb

Function: Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 IQ domain. similarity: Contains 6 LRR (leucine-rich) repeats. subunit: Interacts with CALM1 and CEP110.

Product Specifications

Background

Function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 IQ domain., similarity:Contains 6 LRR (leucine-rich) repeats., subunit:Interacts with CALM1 and CEP110.

UniProt

Q8IW35

Swiss Prot

Q8IW35

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CEP97. AA range:581-630

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

97kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

97kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Recruited at the distal end of the mother centriole by MPHOSPH9. .