Tie-1 rabbit pAb
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
Product Specifications
Background
UniProt
P35590
Swiss Prot
P35590
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TIE1. AA range:851-900
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
130kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein .
Other Product Names
TIE1; TIE; Tyrosine-protein kinase receptor Tie-1
Gene ID (Human)
7075
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GNB1, NT (GNB1, Guanine nucleotide-binding protein G (I) /G (S) /G (T) subunit beta-1, Transducin beta chain 1) (MaxLight 650) discontinued
Human Linker For Activation of T-Cells Family Member 2 (LAT2) ELISA Kit