CD141 rabbit pAb
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
UniProt
P07204
Swiss Prot
P07204
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575
Target
CD141
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
Gene ID (Human)
7056
Available Sizes
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