MtTFA rabbit pAb

This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

Product Specifications

Background

Product Name Alternative

TFAM; TCF6; TCF6L2; Transcription factor A; mitochondrial; mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2

UniProt

Q00059

Swiss Prot

Q00059

Reactivity

Human; Rat; Mouse; ; Bovine

Immunogen

The antiserum was produced against synthesized peptide derived from human TFAM. AA range:131-180

Target

MtTFA

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000; Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

22kd

Storage Conditions

-20°C/1 year

Observed Molecular Weight

22kd

Fragment

IgG

Subcellular Location

Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid .

Other Product Names

TFAM; TCF6; TCF6L2; Transcription factor A; mitochondrial; mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2