RO60 rabbit pAb
Disease: Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign. function: RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the Ro 60 kDa family. similarity: Contains 1 TROVE domain. subunit: Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.
Product Specifications
Background
Product Name Alternative
UniProt
P10155
Swiss Prot
P10155
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360
Target
RO60
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
Other Product Names
Gene ID (Human)
6738
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
