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SEMA3F rabbit pAb

This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],

Product Specifications

Background

This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Synonyms

SEMA3F; Semaphorin-3F; Sema III/F; Semaphorin IV; Sema IV

Gene ID

6405

UniProt

Q13275

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human SEMA3F. AA range:734-783

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA, IHC

Validated Applications

WB,ELISA,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Molecular Weight

88kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7145-1.pdf

Observed Molecular Weight

88 kD

Subcellular Location

Secreted .

Other Product Names

SEMA3F; Semaphorin-3F; Sema III/F; Semaphorin IV; Sema IV

Gene ID (Human)

6405

SwissProt (Human)

Q13275

Available Sizes

Curated Selection

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