NEDL2 rabbit pAb
Function: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. pathway: Protein modification; protein ubiquitination. similarity: Contains 1 C2 domain. similarity: Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. similarity: Contains 2 WW domains. subunit: Interacts with TP73. tissue specificity: Predominantly expressed in adult brain, lung and heart.
Product Specifications
Background
Product Name Alternative
HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2
UniProt
Q9P2P5
Swiss Prot
Q9P2P5
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530
Target
NEDL2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
140-150kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
140-150kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton, spindle .
Other Product Names
HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2
Gene ID (Human)
57520
Available Sizes
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