TMEM16A rabbit pAb

Domain: The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region. function: Acts as a calcium-activated chloride channel. Required for normal tracheal development. similarity: Belongs to the anoctamin family. tissue specificity: Broadly expressed with higher levels in liver and skeletal muscle.

Product Specifications

Background

Domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region., function:Acts as a calcium-activated chloride channel. Required for normal tracheal development., similarity:Belongs to the anoctamin family., tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle.

Product Name Alternative

ANO1; DOG1; ORAOV2; TAOS2; TMEM16A; Anoctamin-1; Discovered on gastrointestinal stromal tumors protein 1; Oral cancer overexpressed protein 2; Transmembrane protein 16A; Tumor-amplified and overexpressed sequence 2

UniProt

Q5XXA6

Swiss Prot

Q5XXA6

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human TM16A. AA range:921-970

Target

TMEM16A

Clonality

Polyclonal

Source

Rabbit

Applications

IF; ELISA

Concentration

1 mg/ml

Dilution

Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. .