PLC β2 rabbit pAb
Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate + H (2)O = 1D-myo-inositol 1, 4, 5-trisphosphate + diacylglycerol. Cofactor: Binds 1 calcium ion per subunit. function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. miscellaneous: The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16. similarity: Contains 1 C2 domain. similarity: Contains 1 PI-PLC X-box domain. similarity: Contains 1 PI-PLC Y-box domain. subunit: Interacts with RAC1.
Product Specifications
Background
UniProt
Q00722
Swiss Prot
Q00722
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human PLC β2.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
150kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
150kD
Fragment
IgG
Subcellular Location
Intracellular, cytosol
Other Product Names
PLCB2; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-2; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2
Gene ID (Human)
5330
Available Sizes
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