ZDHHC2 rabbit pAb

Catalytic activity: Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA. Disease: Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer. Domain: The DHHC domain is required for palmitoyltransferase activity. function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95. similarity: Belongs to the DHHC palmitoyltransferase family. similarity: Contains 1 DHHC-type zinc finger. tissue specificity: Ubiquitously expressed. Reduced expression in colorectal cancers.

Product Specifications

Background

Catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA., disease:Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer., domain:The DHHC domain is required for palmitoyltransferase activity., function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95., similarity:Belongs to the DHHC palmitoyltransferase family., similarity:Contains 1 DHHC-type zinc finger., tissue specificity:Ubiquitously expressed. Reduced expression in colorectal cancers.

Product Name Alternative

ZDHHC2; REAM; REC; ZNF372; Palmitoyltransferase ZDHHC2; Reduced expression associated with metastasis protein; Ream; Reduced expression in cancer protein; Rec; Zinc finger DHHC domain-containing protein 2; DHHC-2; Zinc finger protein 372

UniProt

Q9UIJ5

Swiss Prot

Q9UIJ5

Reactivity

Human; Mouse; Rat; Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human ZDHHC2. AA range:61-110

Target

ZDHHC2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

42kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

42kD

Fragment

IgG

Subcellular Location

Cell junction, synapse, postsynaptic density . Postsynaptic recycling endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Translocates to postsynaptic density when synaptic activity decreases. .