MSH2 rabbit pAb
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
Product Specifications
Background
Product Name Alternative
MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2
UniProt
P43246
Swiss Prot
P43246
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590
Target
MSH2
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome .
Other Product Names
MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2
Gene ID (Human)
4436
Available Sizes
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