STEAP2 rabbit pAb
STEAP2 metalloreductase (STEAP2) Homo sapiens This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
UniProt
Q8NFT2
Swiss Prot
Q8NFT2
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human STEA2. AA range:431-480
Target
STEAP2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .
Other Product Names
Gene ID (Human)
261729
Available Sizes
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