LARG rabbit pAb
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Product Specifications
Background
Product Name Alternative
ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF
UniProt
Q9NZN5
Swiss Prot
Q9NZN5
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498
Target
LARG
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
173kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
173kD
Fragment
IgG
Subcellular Location
Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .
Other Product Names
ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF
Gene ID (Human)
23365
Available Sizes
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