CEP152 rabbit pAb

Centrosomal protein 152 (CEP152) Homo sapiens This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010],

Product Specifications

Background

Centrosomal protein 152 (CEP152) Homo sapiens This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

UniProt

O94986

Swiss Prot

O94986

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CEP152. AA range:841-890

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

140kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

140kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Colocalizes with CDK5RAP2, WDR62 and CEP63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (PubMed:21983783, PubMed:26297806) . Localizes to the deuterosome (By similarity) . Localizes to pericentriolar material (PCM) (PubMed:26337392) . .