Nesprin-3 rabbit pAb
Function: Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system. similarity: Belongs to the nesprin family. similarity: Contains 1 KASH domain. similarity: Contains 2 spectrin repeats. subcellular location: Located at the rough reticulum endoplasmic (RER) in some cells. subunit: Interacts with actin-binding domain of PLEC1/plectin.
Product Specifications
Background
UniProt
Q6ZMZ3
Swiss Prot
Q6ZMZ3
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
115kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
115kD
Fragment
IgG
Subcellular Location
Nucleus outer membrane ; Single-pass type IV membrane protein . Nucleus envelope . Rough endoplasmic reticulum .
Other Product Names
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Gene ID (Human)
161176
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MCL (Macrophage C-type Lectin, C-type Lectin Domain Family 4 Member D, CLR, CLECS89, CLEC4D)
