Eme1 rabbit pAb
This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Product Specifications
Background
Product Name Alternative
EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4
UniProt
Q96AY2
Swiss Prot
Q96AY2
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from Eme1 . at AA range: 250-330
Target
Eme1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
65kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
65kD
Fragment
IgG
Subcellular Location
Nucleus, nucleolus . Recruited to regions of DNA damage in S-phase cells.
Other Product Names
EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4
Gene ID (Human)
146956
Available Sizes
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