Casein Kinase IIβ (phospho Ser209) rabbit pAb
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013],
Product Specifications
Background
Synonyms
CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a
Gene ID
1460
UniProt
P67870
Cellular Locus
Nucleus,nucleoplasm,cytoplasm,cytosol,plasma membrane,protein kinase CK2 complex,PcG protein complex,extracellular exosome,
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CKII-beta around the phosphorylation site of Ser209. AA range:166-215
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
25kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES4865-1.pdf
Observed Molecular Weight
25 kD
Subcellular Location
Nucleus, nucleoplasm, cytoplasm, cytosol, plasma membrane, protein kinase CK2 complex, PcG protein complex, extracellular exosome
Other Product Names
CSNK2B; CK2N; G5A; Casein kinase II subunit beta; CK II beta; Phosvitin; Protein G5a
Gene ID (Human)
1460
SwissProt (Human)
P67870
Available Sizes
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