USP19 rabbit pAb

Catalytic activity: Ubiquitin C-terminal thioester + H (2)O = ubiquitin + a thiol. function: Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. sequence Caution: Translation N-terminally shortened. similarity: Belongs to the peptidase C19 family. similarity: Contains 1 MYND-type zinc finger. similarity: Contains 2 CS domains.

Product Specifications

Background

Catalytic activity:Ubiquitin C-terminal thioester + H (2) O = ubiquitin + a thiol., function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Translation N-terminally shortened., similarity:Belongs to the peptidase C19 family., similarity:Contains 1 MYND-type zinc finger., similarity:Contains 2 CS domains.

UniProt

O94966

Swiss Prot

O94966

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human USP19. AA range:391-440

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

130kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

130kD

Fragment

IgG

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass membrane protein .

Other Product Names

USP19; KIAA0891; ZMYND9; Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19; Zinc finger MYND domain-containing protein 9