PHAPI2 rabbit pAb

Function: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. similarity: Belongs to the ANP32 family. similarity: Contains 4 LRR (leucine-rich) repeats. subcellular location: Accumulates in the nuclei at the S phase. tissue specificity: Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.

Product Specifications

Background

Function:Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity., similarity:Belongs to the ANP32 family., similarity:Contains 4 LRR (leucine-rich) repeats., subcellular location:Accumulates in the nuclei at the S phase., tissue specificity:Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.

Product Name Alternative

ANP32B; APRIL; PHAPI2; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29

UniProt

Q92688

Swiss Prot

Q92688

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human ANP32B. AA range:1-50

Target

PHAPI2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Molecular Weight

29kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

29kD

Fragment

IgG

Subcellular Location

[Isoform 1]: Nucleus . Cytoplasm . Accumulates in the nuclei at the S phase. .; [Isoform 2]: Cytoplasm. Lacks a nuclear localization signal.

Other Product Names

ANP32B; APRIL; PHAPI2; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29