Vav3 rabbit pAb
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
UniProt
Q9UKW4
Swiss Prot
Q9UKW4
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188
Target
Vav3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
98kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
98kD
Fragment
IgG
Subcellular Location
Intracellular, cytosol, plasma membrane, extracellular exosome
Other Product Names
VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Gene ID (Human)
10451
Available Sizes
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