DLC-1 rabbit pAb
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene. [provided by RefSeq, Apr 2010],
Product Specifications
Background
Product Name Alternative
UniProt
Q96QB1
Swiss Prot
Q96QB1
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RHG07. AA range:61-110
Target
DLC-1
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
Other Product Names
Gene ID (Human)
10395
Available Sizes
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