CDKN3 rabbit pAb

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Product Specifications

Background

UniProt

Q16667

Swiss Prot

Q16667

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CDKN3. AA range:31-80

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

23kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

23kD

Fragment

IgG

Subcellular Location

Cytoplasm, perinuclear region .

Other Product Names

CDKN3; CDI1; CIP2; KAP; Cyclin-dependent kinase inhibitor 3; CDK2-associated dual-specificity phosphatase; Cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting protein 2; Kinase-associated phosphatase