IRF-1 rabbit pAb
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
IRF1; Interferon regulatory factor 1; IRF-1
UniProt
P10914
Swiss Prot
P10914
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IRF1. AA range:91-140
Target
IRF-1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
36kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
36kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. .
Other Product Names
IRF1; Interferon regulatory factor 1; IRF-1
Gene ID (Human)
3659
Available Sizes
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