BMP-15 rabbit pAb
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016],
Product Specifications
Background
Product Name Alternative
BMP15; GDF9B; Bone morphogenetic protein 15; BMP-15; Growth/differentiation factor 9B; GDF-9B
UniProt
O95972
Swiss Prot
O95972
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BMP15. AA range:291-340
Target
BMP-15
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
BMP15; GDF9B; Bone morphogenetic protein 15; BMP-15; Growth/differentiation factor 9B; GDF-9B
Gene ID (Human)
9210
Available Sizes
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