GDF-3 rabbit pAb
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],
Product Specifications
Background
Product Name Alternative
GDF3; Growth/differentiation factor 3; GDF-3
UniProt
Q9NR23
Swiss Prot
Q9NR23
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360
Target
GDF-3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
41kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
41kD
Fragment
IgG
Subcellular Location
Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. .
Other Product Names
GDF3; Growth/differentiation factor 3; GDF-3
Gene ID (Human)
9573
Available Sizes
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