Ox40 rabbit pAb
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
UniProt
P43489
Swiss Prot
P43489
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human TNFRSF4. AA range:131-180
Target
Ox40
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
30kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
30kD
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
Gene ID (Human)
7293
Available Sizes
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