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CD66c/d rabbit pAb

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013],

Product Specifications

Background

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]

Product Name Alternative

CEACAM3; CD66D; CGM1; Carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen CGM1; CD66d; CEACAM6; NCA; Carcinoembryonic antigen-related cell adhesion molecule 6; Non-specific crossreacting antigen; Normal cross-reacting antigen; CD66c

UniProt

P40198/P40199

Swiss Prot

P40198/P40199

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM3/CEACAM6. AA range:31-80

Target

CD66c/d

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

30kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

30kD

Fragment

IgG

Subcellular Location

Membrane; Single-pass type I membrane protein.

Other Product Names

CEACAM3; CD66D; CGM1; Carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen CGM1; CD66d; CEACAM6; NCA; Carcinoembryonic antigen-related cell adhesion molecule 6; Non-specific crossreacting antigen; Normal cross-reacting antigen; CD66c

Gene ID (Human)

1084/4680

Available Sizes

Curated Selection

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