AID rabbit pAb
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009],
Product Specifications
Background
Product Name Alternative
AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase
UniProt
Q9GZX7
Swiss Prot
Q9GZX7
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human AICDA. AA range:81-130
Target
AID
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
24kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
24kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Predominantly cytoplasmic (PubMed:21385873) . In the presence of MCM3AP/GANP, relocalizes to the nucleus (By similarity) . .
Other Product Names
AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase
Gene ID (Human)
57379
Available Sizes
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