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Integrin αD rabbit pAb

Integrin subunit alpha D (ITGAD) Homo sapiens This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

Product Specifications

Background

Integrin subunit alpha D (ITGAD) Homo sapiens This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Product Name Alternative

ITGAD; Integrin alpha-D; ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD11d

UniProt

Q13349

Swiss Prot

Q13349

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human ITGAD. AA range:901-950

Target

Integrin αD

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

127kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

127kD

Fragment

IgG

Subcellular Location

Membrane; Single-pass type I membrane protein.

Other Product Names

ITGAD; Integrin alpha-D; ADB2; CD11 antigen-like family member D; Leukointegrin alpha D; CD11d

Gene ID (Human)

3681

Available Sizes

Curated Selection

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