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CD294 rabbit pAb

This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility. [provided by RefSeq, Mar 2011],

Product Specifications

Background

This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]

Product Name Alternative

PTGDR2; CRTH2; DL1R; GPR44; Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD294

UniProt

Q9Y5Y4

Swiss Prot

Q9Y5Y4

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human PTGDR2. AA range:161-210

Target

CD294

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

43kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

43kD

Fragment

IgG

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Internalized receptors colocalized with RAB11A. .

Other Product Names

PTGDR2; CRTH2; DL1R; GPR44; Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD294

Gene ID (Human)

11251

Available Sizes

Curated Selection

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