Jagged1 rabbit pAb
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339
UniProt
P78504
Swiss Prot
P78504
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030
Target
Jagged1
Clonality
Polyclonal
Source
Rabbit
Applications
IF; WB; IHC; ELISA
Concentration
1 mg/ml
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
140kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
140kD
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339
Gene ID (Human)
182
Available Sizes
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