EPAS-1 rabbit pAb
Endothelial PAS domain protein 1 (EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009],
Product Specifications
Background
Product Name Alternative
UniProt
Q99814
Swiss Prot
Q99814
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human EPAS-1 around the non-acetylation site of K385.
Target
EPAS-1
Clonality
Polyclonal
Source
Rabbit
Applications
IF; WB; IHC; ELISA
Concentration
1 mg/ml
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
96kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
96kD
Fragment
IgG
Subcellular Location
Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. .
Other Product Names
Gene ID (Human)
2034
Available Sizes
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