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CD201 rabbit pAb

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013],

Product Specifications

Background

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]

Product Name Alternative

PROCR; EPCR; Endothelial protein C receptor; Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD201

UniProt

Q9UNN8

Swiss Prot

Q9UNN8

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from Endothelial protein C receptor at AA range: 141-190

Target

CD201

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

26kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

26kD

Fragment

IgG

Subcellular Location

Membrane; Single-pass type I membrane protein.

Other Product Names

PROCR; EPCR; Endothelial protein C receptor; Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD201

Gene ID (Human)

10544

Available Sizes

Curated Selection

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