CD1D rabbit pAb

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016],

Product Specifications

Background

Product Name Alternative

CD1D; Antigen-presenting glycoprotein CD1d; R3G1; CD1d

UniProt

P15813

Swiss Prot

P15813

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from Antigen-presenting glycoprotein CD1d at AA range: 161-210

Target

CD1D

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

37kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

37kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Basolateral cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. .