Calbindin D28K rabbit pAb
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015],
Product Specifications
Background
UniProt
P05937
Swiss Prot
P05937
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human CALB1. AA range:191-240
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
30kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
30kD
Fragment
IgG
Subcellular Location
Nucleus, cytosol, axon, dendrite, neuronal cell body, terminal bouton, synapse, extracellular exosome
Other Product Names
CALB1; CAB27; Calbindin; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type
Gene ID (Human)
793
Available Sizes
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