IL-16 rabbit pAb
The protein encoded by this gene is a pleiotropic Cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this Cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The Cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Product Specifications
Background
Product Name Alternative
IL16; Pro-interleukin-16
UniProt
Q14005
Swiss Prot
Q14005
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL16. AA range:1281-1330
Target
IL16
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
140kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
140kD
Fragment
IgG
Subcellular Location
[Interleukin-16]: Secreted.; [Isoform 1]: Cytoplasm .; [Isoform 3]: Cytoplasm. Nucleus.
Other Product Names
IL16; Pro-interleukin-16
Gene ID (Human)
3603
Available Sizes
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