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Chymase rabbit pAb

Chymase 1 (CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015],

Product Specifications

Background

Chymase 1 (CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]

Product Name Alternative

CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I

UniProt

P23946

Swiss Prot

P23946

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Chymase.

Target

Chymase

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

27kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

27kD

Fragment

IgG

Subcellular Location

Secreted. Cytoplasmic granule. Mast cell granules.

Other Product Names

CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I

Gene ID (Human)

1215

Available Sizes

Curated Selection

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