UBE4A rabbit pAb
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011],
Product Specifications
Background
Product Name Alternative
UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A
UniProt
Q14139
Swiss Prot
Q14139
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human UBE4A.
Target
UBE4A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
122kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
122kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Other Product Names
UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A
Gene ID (Human)
9354
Available Sizes
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