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Elmo1 rabbit pAb

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Product Specifications

Background

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Product Name Alternative

ELMO1; KIAA0281; Engulfment and cell motility protein 1; Protein ced-12 homolog

UniProt

Q92556

Swiss Prot

Q92556

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Elmo1. AA range:22-71

Target

Elmo1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

83kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

83kD

Fragment

IgG

Subcellular Location

Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.

Other Product Names

ELMO1; KIAA0281; Engulfment and cell motility protein 1; Protein ced-12 homolog

Gene ID (Human)

9844

Available Sizes

Curated Selection

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