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SSH3 rabbit pAb

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al. 2002 [PubMed 11832213]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .[supplied by OMIM, Mar 2008]

UniProt

Q8TE77

Swiss Prot

Q8TE77

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human SSH3. AA range:357-406

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

74kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

74kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton . Nucleus .

Other Product Names

SSH3; SSH3L; Protein phosphatase Slingshot homolog 3; SSH-like protein 3; SSH-3L; hSSH-3L

Gene ID (Human)

54961

Available Sizes

Curated Selection

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