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PDE4C rabbit pAb

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011],

Product Specifications

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Product Name Alternative

PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21

UniProt

Q08493

Swiss Prot

Q08493

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PDE4C. AA range:291-340

Target

PDE4C

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Molecular Weight

80kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

80kD

Fragment

IgG

Subcellular Location

Cell projection, cilium .

Other Product Names

PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21

Gene ID (Human)

5143

Available Sizes

Curated Selection

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