PBFE rabbit pAb

Catalytic activity: (3S)-3-hydroxyacyl-CoA = trans-2 (or 3)-enoyl-CoA + H (2)O. Catalytic activity: (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA. Catalytic activity: (S)-3-hydroxyacyl-CoA + NAD (+) = 3-oxoacyl-CoA + NADH. Disease: Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease. pathway: Lipid metabolism; fatty acid beta-oxidation. similarity: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. similarity: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. subunit: Monomer. tissue specificity: Liver and kidney. Lower amounts seen in the brain.