NOS2 rabbit pAb

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008],

Product Specifications

Background

UniProt

P35228

Swiss Prot

P35228

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human iNOS. AA range:117-166

Clonality

Polyclonal

Source

Rabbit

Applications

IF; WB; IHC; ELISA

Concentration

1 mg/ml

Dilution

IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

Molecular Weight

131kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

131kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytosol . Localizes as discrete foci scattered throughout the cytosol and in the presence of SPSB1 and SPSB4, exhibits a more diffuse cytosolic localization. .

Other Product Names

NOS2; NOS2A; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2