MINK1 rabbit pAb

This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016],

Product Specifications

Background

UniProt

Q8N4C8

Swiss Prot

Q8N4C8

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MAP4K6. AA range:401-450

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

150kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

150kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cell junction, synapse, postsynaptic density . Cell projection, axon . Cell projection, dendrite .; [Isoform 4]: Golgi apparatus.

Other Product Names

MINK1; B55; MAP4K6; MINK; YSK2; ZC3; Misshapen-like kinase 1; GCK family kinase MiNK; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; Misshapen/NIK-related kinase; Mitogen-activated protein kinase kinase kinase kinase 6