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MerTK rabbit pAb

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) . [provided by RefSeq, Jul 2008]

Product Name Alternative

MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

UniProt

Q12866

Swiss Prot

Q12866

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MERTK. AA range:10-59

Target

MerTK

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Molecular Weight

110kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

110kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Other Product Names

MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

Gene ID (Human)

10461

Available Sizes

Curated Selection

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