MDFI rabbit pAb
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
MDFI; MyoD family inhibitor; Myogenic repressor I-mf
UniProt
Q99750
Swiss Prot
Q99750
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MDFI. AA range:103-152
Target
MDFI
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
25kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
25kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm .
Other Product Names
MDFI; MyoD family inhibitor; Myogenic repressor I-mf
Gene ID (Human)
4188
Available Sizes
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